In December 2019, there was an outbreak of a new coronavirus infection (NCI) COVID-19 in China, which then developed into a pandemic. Almost immediately after the advent of NCI, it became apparent that the presence of chronic diseases, such as diabetes mellitus (DM), plays a key role in the outcome of the disease for infected patients. Based on the results of numerous studies, we concluded that the risks of complications and death in NCI with the presence of diabetes increase significantly. Scientists have shown that, a persona-lized approach, which consists of selecting an optimal treatment regimen for diabetes during the period of NCI, creating the necessary conditions for the prevention of NCI, and developing a strategy for general vaccination of the population is required for the successful management of patients in this cohort.
Objective: to determine an effective strategy for the treatment and prevention of NCI in comorbid patients based on an analysis of domestic and foreign studies.
Methods. In the process of searching for information, articles that were published over the last 4 years (2019–2023) were studied.
A review of more than 90 scientific papers including systematic reviews, meta-analyses, and articles was conducted.
Conclusion. NCI is a serious infectious disease, which, in the presence of comorbid conditions such as diabetes, occurs with an increased risk of mortality and severity of the patient’s condition. To reduce the consequences of the pandemic and effectively prevent new outbreaks, the development of new treatment algorithms and their implementation in clinical practice, early routine monitoring and determination of subsequent vaccination tactics are required.

Keywords: new coronavirus infection, COVID-19, vaccination, diabetes mellitus, prevention