Актовегин: биологический препарат с полувековой историей

Buchmayer F., Pleiner J., Elmlinger M.W., Lauer G., Nell G., Sitte H.H.

Актовегин представляет собой биологический препарат: гемодиализат телячьей крови, который получают из природного источника. В основе его лечебного действия лежит ряд механизмов, приводящих к общему результату: усилению внутриклеточного метаболизма, связанного с инсулиноподобным действием инозитолфосфоолигосахаридов. Актовегин помогает при нарушениях кровообращения и трофики головного мозга, нарушениях периферического кровотока и связанных с этим заболеваниях, трансплантации кожи и лечении ран. В данной статье рассматриваются механизмы действия Актовегина и его активность в различных патологических ситуациях.


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Об авторах / Для корреспонденции

1 Center for Physiology and Pharmacology, Institute of pharmacology, Medical University of Vienna, Vienna, Austria
2 Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria
3 Nycomed GmbH, Biomarker Development, Konstanz, Germany

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