Возможности применения инсулина детемир при лечении сахарного диабета у беременных: доказанные преимущества и перспективы использования


Л.А. Руяткина (1), М.Ю. Сорокин (2)

1) ГБОУ ВПО «Новосибирский государственный медицинский университет» Минздрава РФ, Новосибирск; 2) МБУЗ НСО Городская клиническая больница № 1, Новосибирск
Хороший гликемический контроль в течение всей беременности обеспечивает снижение риска материнских, фетальных и неонатальных осложнений. Поэтому инсулинотерапия является основой терапии сахарного диабета 1 и 2 типов у беременных женщин, а также гестационного сахарного диабета. Цель обзора – анализ эффективности и безопасности применения инсулина детемир – первого базального аналога инсулина, одобренного к применению во время беременности (категория В, FDA). Улучшенные фармакокинетический и фармакодинамический профииь, низкая вариабельность действия и большая предсказуемость клинического эффекта инсулина детемир предоставляют оптимальный контроль гликемии при низком риске гипогликемий и нейтральном влиянии на массу тела. Клинические преимущества инсулина детемир подтверждены результатами клинических исследований у беременных женщин с диабетом, что позволяет рекомендовать инсулин детемир в качестве препарата первой линии при выборе инсулина длительного действия для лечения сахарного диабета у беременных.

Литература


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Об авторах / Для корреспонденции


Л.А. Руяткина – д.м.н., проф., ГБОУ ВПО «Новосибирский государственный медицинский университет» Минздрава РФ, Новосибирск
М.Ю. Сорокин – МБУЗ НСО Городская клиническая больница № 1, Новосибирск


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