Hormonal-metabolic Parameters In Young Men With Obesity Manifesting At Puberty


A.F. Verbovoy’, Yu.A. Dolgikh

Department of endocrinology Samara state medical University, Samara.
65 young men with obesity manifesting in puberty, average age 19,22 ± 0,26 years, were examined with the aim of evaluation the relationship of leptin, resistin and insulin resistance. Control group included 17 healthy young men, average age 22 ± 0,72 years. It was found that young men with obesity had abdominal type of fat distribution and atherogenic dyslipidemia associated with abdominal fat distribution. In the group of obese patients, insulin resistance and compensatory hyperinsulinemia were found. There was significant increase of leptin levels. Direct correlation between leptin, body mass index, waist and hip circumference were observed. In addition, a direct correlation between leptin levels and insulin and resistin levels was revealed.

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