Modern practical healthcare has many unsolved problems regarding diagnostics, including differential ones, of various nosologies, as well as optimal tactics for managing comorbid patients; in connection with which it is important to use an individual approach to each patient. The presented clinical case demonstrates the development of pancreatogenic diabetes mellitus due to exacerbation of chronic pancreatitis. The complexity of diagnostics consisted of understanding the true cause of the increase in blood glucose levels. It should be emphasized that newly diagnosed hyperglycemia requires consultation by an endocrinologist, but hyperglycemia is not always a direct cause of the deterioration of the patient’s condition. The final clinical diagnosis was established by a consultation involving a therapist, endocrinologist, gastroenterologist, emergency physician and nephrologist. Based on the results of the consultation, complex therapy was prescribed to reduce the severity of inflammatory processes in the pancreas, liver and kidneys, normalize blood glucose levels, and reduce symptoms. This clinical case shows importance of a multidisciplinary approach to the patient is, since most often older patients are comorbid patients. The lack of regular monitoring and timely correction of treatment can significantly worsen the quality of life and reduce the life expectancy of patients.

Keywords: pancreatogenic diabetes mellitus, comorbidity, chronic pancreatitis, clinical case