Русский
Effective treatment of exogenous-constitutional obesity in a young patient: a description of a clinical case
DOI: https://dx.doi.org/10.18565/pharmateca.2022.11-12.89-94
I.A. Kurnikova, Sh.G. Gulova, N.O. Danilina, A.S. Klimenko, D.D. Chentsova
1) RUDN University, Moscow, Russia; 2) CDC RUDN, Moscow, Russia
Background. Modern approaches to diagnosing systemic diseases include not only clinical and laboratory characteristics, but methods for assessing regulatory disorders. Among these diseases is obesity, which is characterized by not only metabolic disorders, but also violations of vegetative regulatory mechanisms.
Description of the clinical case. In the presented clinical case, a 19-year-old patient diagnosed with III degree exogenous-constitu- tional obesity and severe disorders of autonomic regulation was prescribed treatment with the inclusion of centrally acting drugs (mono- amine reuptake inhibitor) precisely for the purpose of correcting regulatory disorder. Data obtained indicated the sufficient effectiveness of such treatment, and the formation of eutonia allows considering this as a one of the possible mechanisms for the implementation of the action of the drug in young people.
Conclusion. Whether the normalization of autonomic balance is one of the mechanisms for realizing the effect of monoamine reuptake inhibitors, or is it a consequence of ongoing processes, is still difficult to say, but assessing the state of regulatory processes, at least to determine the indications for prescribing a particular therapy option, as well as monitoring the effectiveness of the treatment, is an promising direction. The obtained preliminary results indicate the need for further research.
Description of the clinical case. In the presented clinical case, a 19-year-old patient diagnosed with III degree exogenous-constitu- tional obesity and severe disorders of autonomic regulation was prescribed treatment with the inclusion of centrally acting drugs (mono- amine reuptake inhibitor) precisely for the purpose of correcting regulatory disorder. Data obtained indicated the sufficient effectiveness of such treatment, and the formation of eutonia allows considering this as a one of the possible mechanisms for the implementation of the action of the drug in young people.
Conclusion. Whether the normalization of autonomic balance is one of the mechanisms for realizing the effect of monoamine reuptake inhibitors, or is it a consequence of ongoing processes, is still difficult to say, but assessing the state of regulatory processes, at least to determine the indications for prescribing a particular therapy option, as well as monitoring the effectiveness of the treatment, is an promising direction. The obtained preliminary results indicate the need for further research.
About the Autors
Corresponding author: Irina A. Kurnikova, Dr. Sci. (Med.), Professor at the Department of Hospital Therapy with Courses of Endocrinology, Hematology and Clinical Laboratory Diagnostics, Medical Institute, Peoples’ Friendship University of Russia, Moscow, Russia; curnikova@yandex.ru
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