Is non-alcoholic fatty liver disease a consequence of obesity and a predictor of diabetes?


N.I. Volkova, S.O. Panenko, A.O. Golubeva

Rostov State Medical University, Department of Internal Medicine № 3, Rostov-on-Don, Russia
Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease that tends to annually increase in incidence along with obesity. The presence of NAFLD is associated with the development of fibrosis, cirrhosis, liver cancer, as well as a high incidence of cardiovascular diseases. At the same time, the occurrence of type 2 diabetes mellitus (DM2) is certainly associated with NAFLD; moreover, the combination of these diseases contributes to their accelerated progressive course. This review was aimed to the evaluation of the pathogenetic relationship of NAFLD, DM2 and obesity in order to develop the most appropriate tactics for the treatment of comorbidity.

About the Autors

Corresponding author: Stanislav O. Panenko, Postgraduate Student at the Department of Internal Medicine № 3, Rostov State Medical University, Rostov-on-Don, Russia;

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