Carbohydrate metabolism disorders and osteoporosis


DOI: https://dx.doi.org/10.18565/pharmateca.2021.12.107-112

N.S. Alekseeva

Novokuznetsk State Institute for Advanced Training of Doctors – Branch Campus of the Russian Medical Academy of Continuous Professional Education, Novokuznetsk, Russia
Diabetes mellitus (DM) and osteoporosis are two socially significant and mutual burdened diseases that have reached the scale of epidemic. These diseases are closely related and have common pathogenetic mechanisms of development. However, problems of insufficient prevention and diagnosis of both prediabetes and osteopenic conditions remain. Timely therapy for prediabetes with metformin can have a beneficial effect on both the patient’s glycemic and metabolic status, and the state of bone tissue. When choosing a hypoglycemic therapy, it should be taking into account that drugs can have both a negative effect on the state of bone tissue (insulin, thiazilidones, sulfonylureas), and neutral (glucagon-like peptide-1 receptor agonists) or a positive effect (metformin, dipeptidyl peptidase-4 inhibitors).

About the Autors


Corresponding author: Natalya S. Alekseeva, Dr. Sci. (Med.), Associate Professor, Head of the Department of General Medical Practice (Family Doctor), Novokuznetsk State Institute for Advanced Training of Doctors - Branch Campus of the Russian Medical Academy of Continuous Professional Education, Novokuznetsk, Russia; natali-sim82@mail.ru; ORCID: https://orcid.org/0000-0002-9122-1735, eLibrary SPIN: 5620-4830


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