HYBRID SCHEME OF ERADICATION THERAPY OF HELICOBACTER PYLORI INFECTION: SYSTEMATIZATION OF LITERATURE DATA


G.L.Yurenev, D.N. Andreev, E.V. Partsvaniya-Vinogradova, D.T. Dicheva

FSBEI HE “Moscow State Medical Stomatological University n.a. A.I. Evdokimov” of RMH, Moscow
Reduced effectiveness of standard schemes of eradication therapy (ET) of Helicobacter pylori infection, correlating with an increase in antibiotic resistance of a microorganism, determines the feasibility of the development and a comprehensive evaluation of alternative variants of ET. The hybrid ET, proposed in 2011 by Chinese researchers and successfully tested in a number of countries in Asia, Europe and the Middle East, has attracted wide attention of the international gastroenterological community through a combination of efficacy and acceptable safety. This review systematizes literature data on the hybrid scheme of ET, including its efficacy, safety, tolerability, and its current place as a method of prevention and treatment of H. pylori-associated diseases.

About the Autors


D.N. Andreev – PhD, Teaching Assistant at the Department of Propedeutics of Internal Diseases and Gastroenterology, Scientific Researcher at the Laboratory of Functional Methods of Examination in Gastroenterology FSBEI HE MSMSU n.a. A.I. Evdokimov of RMH, Moscow; e-mail: dna-mit8@mail.ru


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