Ошибки применения лекарственных средств как фактор риска развития лекарственно-индуцированных заболеваний


DOI: https://dx.doi.org/10.18565/pharmateca.2021.11.84-94

Д.А. Сычев (1), О.Д. Остроумова (1, 2), А.И. Кочетков (1), А.П. Переверзев (1), Т.М. Остроумова (2), М.В. Клепикова (1), Е.Ю. Эбзеева (1)

1) Российская медицинская академия непрерывного профессионального образования, Москва, Россия; 2) Первый Московский государственный медицинский университет им. И.М. Сеченова (Сеченовский Университет), Москва, Россия
Ошибки применения лекарственных средств (ОПЛС) способны существенно ухудшать прогноз пациента, наносить тяжелый вред здоровью, повышать показатели смертности, а также служить значимым фактором риска развития лекарственно индуцированных заболеваний. С ОПЛС связана приблизительно треть побочных эффектов на фоне лекарственной терапии. ОПЛС могут возникать на разных этапах организации медикаментозной терапии: при формировании назначений врачом, переносе медицинским персоналом назначений в сопутствующую медицинскую документацию, выдаче и дозировании лекарственного средства (ЛС), его производстве, хранении и подготовке к использованию, а также непосредственно при применении и введении препарата в организм пациента. Как показывают исследования, с ОПЛС ассоциируются такие факторы, как информация, относящаяся к истории болезни пациента, сами ЛС, взаимодействие между медицинскими работниками с целью передачи информации о ЛС, номенклатура и упаковка ЛС, хранение, сохранность и стандартизация ЛС, приобретение, использование и мониторинг устройств для приема ЛС, факторы окружающей среды, компетентность и образование медицинского персонала и пациента, процессы управления качеством и рисками фармакотерапии. Ввиду исключительной значимости ОПЛС в развитии ятрогений на сегодняшний день разрабатываются и тестируются на практике различные походы к профилактике и минимизации таких ошибок. К данным подходам относятся согласование и выверка фармацевтом применяемых ЛС, использование компьютеризированных систем анализа применяемых ЛС и ввода назначений, которые сделал лечащий врач, в ряде случаев с инструментом поддержки принятия клинического решения, партнерское сотрудничество с фармацевтами и междисциплинарная кооперация, обучение врачей и пациентов, привлечение специально подготовленных экспертов в области фармакологии и фармакотерапии, автоматизированная система выдачи лекарственных препаратов, использование электронного листа назначений и применение методов облегчения раздачи ЛС пациентам. Исходя из анализа доступной литературы можно сделать вывод, согласно которому в настоящее время так или иначе необходима дальнейшая активная научно-исследовательская и практическая работа по максимальному снижению распространенности ОПЛС ввиду их принципиальной роли в аспектах безопасности фармакотерапии.

Литература


1. Tisdale J.E., Miller D.A. Drug-induced diseases: prevention, detection, and management. 3rd ed. Bethesda, Md.: American Society of Health-System Pharmacists; 2018. 1399 р.


2. Переверзев А.П., Зырянов С.К., Гущина Ю.Щ. Современные методы идентификации нежелательных явлений, вызванных ошибками применения лекарственных препаратов. Безопасность и риск фармакотерапии. 2016;(4):11–6.


3. Кузьмина А.В., Асецкая И.Л., Поливанов В.А., Зырянов С.К. Медицинские ошибки при применении лекарственных препаратов в практическом здравоохранении. Практическая пульмонология. 2016;(3):76–83.


4. Kapaki V. The Anatomy of Medication Errors. In: Vignettes in Patient Safety. Ed. by S.P. Stawicki, M.S. Firstenberg. 2019. Volume 4. doi: 10.5772/intechopen.79778. URL: https://www.intechopen.com/books/vignettes-in-patient-safety-volume-4/the-anatomy-of-medication-errors (accessed 2021 Sep 07).


5. National Coordinating Council for Medication Error Reporting and Prevention. About medication errors. URL: http://www.nccmerp. org/about-medication-errors (accessed 2021 Sep 07).


6. Решение Совета Евразийской экономической комиссии от 03.11.2016 № 87 об «Утверждении Правил надлежащей практики фармаконадзора Евразийского экономического союза». Ссылка активна на 07.09.2021.


7. McCarthy A.M., Kelly M.W., Reed D. Medication administration practices of school nurses. J School Health. 2000;70(9):371–76. Doi: 10.1111/j.1746-1561.2000.tb07277.x.


8. Mihailidis A., Krones L., Boger J. Assistive computing devices: A pilot study to explore nurses’ preferences and needs. Computers, Informatics, Nursing. 2006;24(6):328–36. Doi: 10.1097/00024665-200611000-00007.


9. Hashemi F. Response ethics to nursing errors. J Med Ethics Hist Med. 2007;4:31–46.


10. Cuzzolin L., Atzei A., Fanos V. Off-label and unlicensed prescribing for newborns and children in different settings: A review of the literature and a consideration about drug safety. Exp Opin Drug Safety. 2006;5(5):703–18 Doi: 10.1517/14740338.5.5.703.


11. Lindell-Osuagwu L., Korhonen M.J., Saano S., et al. Off-label and unlicensed drug prescribing in three paediatric wards in Finland and review of the international literature. J Clin Pharm Ther. 2009;34(3):277–87. Doi: 10.1111/j.1365-2710.2008.01005.x.


12. Pandolfini C., Bonati M. A literature review on off-label drug use in children. Eur J Pediatr. 2005;164(9):552–58. Doi: 10.1007/s00431-005-1698-8.


13. Jiménez Muñioz A.B., Muiño Miguez А., Rodriguez Prez М.Р., Medication error prevalence. Int J Health Care Quality Assurance. 2010;23(3):328–38. Doi: 10.1108/09526861011029389.


14. Bates D.W., Cullen D.J., Laird N., et al. Incidence of adverse drug events and potential adverse drug events. Implications for prevention. ADE Prevention Study Group. J Am Med Associat. 1995;274(1):29–34.


15. Kohn L.T., Corrigan J.M., Donaldson M.S., ed. Institute of Medicine (US) Committee on Quality of Health Care in America. To Err is Human: Building a Safer Health System. Washington (DC): National Academies Press (US); 2000. 312 р. Doi: 10.17226/9728.


16. Holquist C. Medication errors: an FDA perspective. European Union Regulatory Workshop on Medication Errors, 2013. URL: http://www.ema.europa.eu/docs/en_GB/document_library/Presentation/2013/03/WC500139886.pdf Accessed September, 07, 2021.


17. Thomas A.N., Panchagnula U. Medication-related patient safety incidents in critical care: A review of reports to the UK National Patient Safety Agency. Anaesth. 2008;63(7):726–33. Doi: 10.1111/j.1365-2044.2008.05485.x.


18. Budnitz D.S., Pollock D.A., Weidenbach K.N., et al. National surveillance of emergency department visits for outpatient adverse drug events. J Am Med Associat. 2006;296(15):1858–66. Doi: 10.1001/jama.296.15.1858.


19. Alqenae F.A., Steinke D., Keers R.N. Prevalence and Nature of Medication Errors and Medication-Related Harm Following Discharge from Hospital to Community Settings: A Systematic Review. Drug Saf. 202;43(6):517–37. Doi: 10.1007/s40264-020-00918-3.


20. Tang F.I., Sheu S.-J., Yu S., et al. Nurses relate the contributing factors involved in medication errors. J Clin Nursing. 2007;16(3):447–57. Doi: 10.1111/j.1365-2702.2005.01540.x.


21. Keohane C.A., Bates D.W. Medication safety. Obstetr Gynecol Clin North Am. 2008;35(1):37–52 (viii). Doi: 10.1016/j.ogc.2007.12.002.


22. Bates D.W., Boyle D.L., Vander Vliet M.B., et al. Relationship between medication errors and adverse drug events. J General Int Med. 1995;10(4):199–205. Doi: 10.1007/BF02600255.


23. Лепахин В.К., Астахова А.В., Овчинникова Е.А., Овчинникова Л.К. Врачебные ошибки как причина осложнений лекарственной терапии. Качественная клиническая практика. 2002;(1):71–7.


24. Brosch S. Good practice: MedDRA coding of case reports resulting in harm. Session 2 Reporting. European Medicines Agency. Medication-errors workshop. London, 28 February–1 March 2013. URL: http://www.ema.europa.eu/docs/en_GB/document_library/Presentation/2013/03/WC500139872.pdfAccessed September, 07, 2021.


25. Белоусов Ю.Б., Кукес В.Г., Лепахин В.К., Петров В.И. Клиническая фармакология. Национальное руководство. М., 2014. 976 c.


26. Tackling medication errors: European Medicines Agency workshop calls for coordinated EU approach. Press release. 2013. URL: http://www.ema.europa.eu/ema/index.jsp?curl=pages/news_and_events/news/2013/03/news_detail_001729.jsp&mid=WC0b01ac058004d5c1 Accessed September, 07, 2021.


27. Meyer-Massetti C., Hofstetter V., Hedinger-Grogg B., et al. Medication-related problems during transfer from hospital to home care: baseline data from Switzerland. Int J Clin Pharm. 2018;40(6):1614–20. Doi: 10.1007/s11096-018-0728-3.


28. Parekh N., Ali K., Stevenson J.M., et al. Incidence and cost of medication harm in older adults following hospital discharge: a multicentre prospective study in the UK. Br J Clin Pharmacol. 2018;84(8):1789–97. Doi: 10.1111/bcp.13613.


29. Lisby M., Nielsen L., Brock B., Mainz J. How are medication errors defined: a systematic literature review of definitions and characteristics. Int J Qual Health Care. 2010;22(6):507–18. Doi: 10.1093/intqhc/mzq059.


30. Allan E., Barker K. Fundamentals of medication error in research. Am J Hosp Pharm. 1990;47(3):555–71.


31. Duggan C., Bates I., Hough J. Discrepancies in prescribing: where do they occure? Pharm J. 1996;265:65–7.


32. Duggan C., Feldman R., Hough J., Bates I. Reducing adverse prescribing discrepancies following hospital discharge. Int J Pharm Pract. 1998;6(2):77–82. Doi: 10.1111/j.2042-7174.1998.tb00920.x.


33. Forster A.J., Murff H.J., Peterson J.F., et al. Adverse drug events occurring following hospital discharge. J Gen Intern Med. 2005;20(4):317–23. Doi: 10.1111/j.1525-1497.2005.30390.x.


34. Gray S., Mahoney J., Blough D. Adverse drug events in elderly patients receiving home health services following hospital discharge. Ann Pharmacother. 1999;33(1):1147–53. Doi: 10.1345/aph.19036.


35. Heyworth L., Paquin A.M., Clark J., et al. Engaging patients in medication reconciliation via a patient portal following hospital discharge. J Am Med Inform Assoc. 2014;21(е1):157–62. Doi: 10.1136/amiajnl-2013-001995.


36. Ahmad A., Mast M.R., Nijpels G., et al. Identification of drug-related problems of elderly patients discharged from hospital. Patient Prefer Adher. 2014;8:155–65. Doi: 10.2147/PPA.S48357.


37. Hockly M., Williams S., Allen M. Transfer of care: a randomised control trial investigating the effect of sending the details of patients’ discharge medication to their community pharmacist on discharge from hospital. Int J Pharm Pract. 2018;26(2):174–82. Doi: 10.1111/ijpp.12364.


38. Holdhus H., Bovre K., Mathiesen L., et al. Limited effect of structured medication report as the only intervention at discharge from hospital. Pharm. 2019;26(2):101–5. Doi: 10.1136/ejhpharm-2017-001371.


39. Kanaan A.O., Donovan J.L., Duchin N.P., et al. Adverse drug events after hospital discharge in older adults: types, severity, and involvement of beers criteria medications. J Am Geriatr Soc. 2013;61(11):1894–99. Doi: 10.1111/jgs.12504.


40. Letrilliart L., Hanslik T., Biour M. Postdischarge adverse drug reactions in primary care originating from hospital care in France. Drug Saf. 2001;24(10):781–93. Doi: 10.2165/00002018-200124100-00006.


41. Marusic S., Sicaja M., Neto P., et al. Adverse drug reactions in elderly patients following discharge from an internal medicine clinic. Int J Clin Pharmacol Ther. 2014;52(10):906–13. Doi: 10.5414/CP202041.


42. Mesteig M., Helbostad J.L., Sletvold O., et al. Unwanted incidents during transition of geriatric patients from hospital to home: a prospective observational study. BMC. Health Serv Res. 2010;10:1–9. Doi: 10.1186/1472-6963-10-1.


43. Midlov P., Bahrani L., Seyfali M., et al. The effect of medication reconciliation in elderly patients at hospital discharge. Int J Clin Pharm. 2012;34(1):113–19. Doi: 10.1007/s11096-011-9599-6.


44. Al-Ghamdi S.A., Mahmoud M.A., Alammari M.A., et al. The outcome of pharmacist counseling at the time of hospital discharge: an observational nonrandomized study. Ann Saudi Med. 2012;32(5):492–97. Doi: 10.5144/0256-4947.2012.492.


45. Osorio S.N., Abramson E., Pfoh E.R., et al. Risk factors for unexplained medication discrepancies during transitions in care. Fam Med. 2014;46(8):587–96.


46. Riordan C.O., Delaney T., Grimes T. Exploring discharge prescribing errors and their propagation post-discharge: an observational study. Int J Clin Pharm. 2016;38(5):1172–81. Doi: 10.1007/s11096-016-0349-7.


47. Salameh L.K., Abu Farha R.K., Abu Hammour K.M., Basheti I.A. Impact of pharmacist’s directed medication reconciliation on reducing medication discrepancies during transition of care in hospital setting. J Pharm Health Serv Res. 2019;10(1):149–56. Doi: 10.1111/jphs.12261.


48. Schnipper J., Kirwin J., Cotugno M., et al. Role of pharmacist counseling in preventing adverse drug events after hospitalization. Arch Intern Med. 2006;166(5):565–71. Doi: 10.1001/archinte.166.5.565.


49. Solanki R., Mondal N., Mahalakshmy T., Bhat V. Medication errors by caregivers at home in neonates discharged from the neonatal intensive care unit. Arch Dis Child. 2017;102(7):651–54. Doi: 10.1136/archdischild-2016-311877.


50. Al-Hashar A., Al-Zakwani I., Eriksson T., et al. Impact of medication reconciliation and review and counselling, on adverse drug events and healthcare resource use. Int J Clin Pharm. 2018;40(5):1154–64. Doi: 10.1007/s11096-018-0650-8.


51. Bergkvist A., Midlov P., Hцglund P., et al. Improved quality in the hospital discharge summary reduces medication errors-LIMM: Landskrona Integrated Medicines Management. Eur J Clin. Pharmacol. 2009;65(10):1037–46. Doi: 10.1007/s00228-009-0680-1.


52. Bonaudo M., Martorana M., Dimonte V., et al. Medication discrepancies across multiple care transitions: a retrospective longitudinal cohort study in Italy. PLoS One. 2018;13(1):1–13. Doi: 10.1371/journal.pone.0191028.


53. Buajordet I., Wesenberg F., Bros O. Adverse drug events in children during hospitalization and after discharge in a Norwegian University Hospital. Acta Paediatr. 2002;91(2):88–94. Doi: 10.1080/080352502753458021.


54. Alldred D., Standage P., Zermansky A. Medication discrepancies and errors postdischarge from hospital: a pilot evaluation. Int J Pharm. Pract. 2010;18:22. Doi:10.1111/j.2042-7174.2010.00020.x.


55. Wilting I., Maanen A.C.D.-V., Jansen P.A.F., et al. The effect of a multicomponent transitional pharmaceutical care intervention on the incidence and nature of unintentional medication discrepancies in geriatric patients after hospital discharge. Eur Geriatr Med. 2012;3:S118. Doi: 10.1016/j.eurger.2012.07.283.


56. Wijekoon C.N., Shanika L.G.T., Jayamanne S., et al. Adverse drug reactions in a cohort of Sri Lankan patients with non-communicable chronic diseases. Clin Ther. 2017;39(8):e80. Doi: 10.1016/j.clinthera.2017.05.246.


57. Claeys C., Senterre C., Neve J., et al. Effect of a clinical pharmacist intervention on unintentional medication discrepancies after discharge: a prospective cohort study. Int J Clin. Pharm. 2013;35(6):1286–87.


58. Donovan J., Kanaan A., Tija J., Al E. Identification of adverse drug events post-hospital discharge in a geriatric population. Pharmacother. 2012;32:E255.


59. Huynh C., Jani Y., Wong I.C.K., et al. Clinical significance of medication discrepancies in children post hospital discharge across five hospitals in England. Int J Pharm Pract. 2013;21(Suppl. S2):10–6. Doi: 10.1111/ijpp.12063_2.


60. Leland J., Cariaga J., Davis D., Al E. Home based transitional care. J Am Geriatr Soc. 2012;60:S212–3.


61. Patel K., Wright D.J., Desborough J. Effectiveness of electronic discharge and handover system at Basildon and Thurrock University Hospitals NHS Foundation Trust: a service evaluation. Int J Pharm Pract. 2011;19:34.


62. Pourrat X., Roux C., Bouzige B., et al. Impact of drug reconciliation at discharge and communication between hospital and community pharmacists on drugrelated problems: a randomized controlled trial. Int J Clin Pharm. 2017;39:212–3.


63. Karthikeyan M., Balasubramanian T., Khaleel M.I., et al. A Systematic Review on Medication Errors. Int. J. Drug Devel. Res. 2015;7(4):9–11.


64. Hartwig S.C., Denger S.D., Schneider P.J. Severity-indexed, incident report-based medication error-reporting program. Am J Hospital Pharm. 1991;48(12):2611–16.


65. Cousins D.D., Heath W.M. The National Coordinating Council for Medication Error Reporting and Prevention: Promoting patient safety and quality through innovation and leadership. Joint Commis. J Qual Patient Saf. 2008;34(12):700–2. Doi: 10.1016/s1553-7250(08)34091-4.


66. Carney S.L. Medication accuracy and general practitioner referral letters. Intern Med J. 2006;36(2):132–34. Doi: 10.1111/j.1445-5994.2006.01022.x.


67. Berman A. Reducing medication errors through naming, labeling, and packaging. J Med Syst. 2004;28(1):9–29. Doi: 10.1023/b:joms.0000021518.60670.10.


68. Аляутдин Р.Н., Переверзев А.П., Романов Б.К., Бунятян Н.Д. К вопросу о влиянии названий и маркировки лекарственных средств на риск развития медицинских ошибок. Безопасность и риск фармакотерапии. 2014;3(4):15–9.


69. Manias E., Kusljic S., Wu A. Interventions to reduce medication errors in adult medical and surgical settings: a systematic review. Ther Adv Drug Saf. 2020;11:2042098620968309. Doi: 10.1177/2042098620968309.


70. Batra R., Wolbach-Lowes J., Swindells S., et al. Impact of an electronic medical record on the incidence of antiretroviral prescription errors and HIV pharmacist reconciliation on error correction among hospitalized HIV-infected patients. Antivir Ther. 2015;20(5):555–59. Doi: 10.3851/IMP2930.


71. Cadman B., Wright D., Bale A., et al. Pharmacist provided medicines reconciliation within 24 hours of admission and on discharge: a randomised controlled pilot study. BMJ. Open. 2017;7(3):e013647. Doi: 10.1136/bmjopen-2016-013647.


72. Allison G.M., Weigel B., Holcroft C. Does electronic medication reconciliation at hospital discharge decrease prescription medication errors? Int J Health Care Qual Assur. 2015;28(6):564–73. Doi: 10.1108/IJHCQA-12-2014-0113.


73. Smith K.J., Handler S.M., Kapoor W.N., et al. Automated Communication Tools and Computer-Based Medication Reconciliation to Decrease Hospital Discharge Medication Errors. Am J Med Qual. 2016;31(4):315-–22. Doi: 10.1177/1062860615574327.


74. Schnipper J.L., Mixon A., Stein J., et al. Effects of a multifaceted medication reconciliation quality improvement intervention on patient safety: final results of the MARQUIS study. BMJ. Qual Saf. 2018;27(12):954–64. Doi: 10.1136/bmjqs-2018-008233.


75. Hernandez F., Majoul E., Montes-Palacios C., et al. An observational study of the impact of a computerized physician order entry system on the rate of medication errors in an orthopaedic surgery unit. PLoS One. 2015;10(7):e0134101. Doi: 10.1371/journal.pone.0134101.


76. Milani R.V., Oleck S.A., Lavie C.J. Medication errors in patients with severe chronic kidney disease and acute coronary syndrome: the impact of computer-assisted decision support. Mayo Clin Proc. 2011;86(12):1161–64. Doi: 10.4065/mcp.2011.0290.


77. Pettit N.N., Han Z., Choksi A., et al. Reducing medication errors involving antiretroviral therapy with targeted electronic medical record modifications. AIDS Care. 2019;31(7):893–96. Doi: 10.1080/09540121.2019.1566512.


78. Shawahna R., Rahman N.U., Ahmad M., et al. Electronic prescribing reduces prescribing error in public hospitals. J Clin Nurs. 2011;20(21–22):3233–45. Doi: 10.1111/j.1365-2702.2011.03714.x.


79. van Doormaal J.E., van den Bemt P.M., Zaal R.J., et al. The influence that electronic prescribing has on medication errors and preventable adverse drug events: an interrupted time-series study. J Am Med Inform Assoc. 2009;16(6):816–25. Doi: 10.1197/jamia.M3099.


80. García-Molina Sáez C., Urbieta Sanz E., Madrigal de Torres M., et al. Computerized pharmaceutical intervention to reduce reconciliation errors at hospital discharge in Spain: an interrupted time-series study. J Clin Pharm Ther. 2016;41(2):203–8. Doi: 10.1111/jcpt.12365.


81. Hassan Y., Al-Ramahi R.J., Aziz N.A., Ghazali R. Impact of a renal drug dosing service on dose adjustment in hospitalized patients with chronic kidney disease. Ann Pharmacother. 2009;43(10):1598–605. Doi: 10.1345/aph.1M187.


82. Liedtke M.D., Tomlin C.R., Skrepnek G.H., et al. HIV Pharmacist’s Impact on Inpatient Antiretroviral Errors. HIV Med. 2016;17(10):717–23. Doi: 10.1111/hiv.12375.


83. Gursanscky J., Young J., Griffett K., et al. Benefit of targeted, pharmacist-led education for junior doctors in reducing prescription writing errors – a controlled trial. J Pharm Pract Res. 2018;48(6):26–35. Doi: 10.1002/jppr.1330.


84. Weingart S.N., Toth M., Eneman J., et al. Lessons from a patient partnership intervention to prevent adverse drug events. Int J Qual Health Care. 2004;16(6):499–507. Doi: 10.1093/intqhc/mzh083.


85. Baqir W., Jones K., Horsley W., et al. Reducing unacceptable missed doses: pharmacy assistant-supported medicine administration. Int J Pharm Pract. 2015;23(5):327–32. Doi: 10.1111/ijpp.12172.


86. Greengold N.L., Shane R., Schneider P., et al. The impact of dedicated medication nurses on the medication administration error rate: a randomized controlled trial. Arch Intern Med. 2003;163(19):2359–67. Doi: 10.1001/archinte.163.19.2359.


87. Nguyen E.E., Connolly P.M., Wong V. Medication safety initiative in reducing medication errors. J Nurs Care Qual. 2010;25(3):224–30. Doi: 10.1097/ncq.0b013e3181ce3ae4.


88. Schneider P.J., Pedersen C.A., Montanya K.R., et al. Improving the safety of medication administration using an interactive CD-ROM program. Am J Health Syst Pharm. 2006;63(1):59–64. Doi: 10.2146/ajhp040609.


89. Dean B., Barber N. The effects of a patient’s own drugs scheme on the incidence and severity of medication administration errors. Int J Pharm Pract. 2000;8(3):209–16. Doi: 10.1111/j.2042-7174.2000.tb01007.x.


90. Schimmel A.M., Becker M.L., van den Bout T., et al. The impact of type of manual medication cart filling method on the frequency of medication administration errors: a prospective before and after study. Int J Nurs Stud. 2011;48(7):791–97. Doi: 10.1016/j.ijnurstu.2010.12.007.


91. Cousein E., Mareville J., Lerooy A., et al. Effect of automated drug distribution systems on medication error rates in a short-stay geriatric unit. J Eval Clin Pract. 2014;20(5):678–84. Doi: 10.1111/jep.12202.


92. Grimes T.C., Deasy E., Allen A., et al. Collaborative pharmaceutical care in an Irish hospital: uncontrolled before-after study. BMJ. Qual Saf. 2014;23(7):574–83. Doi: 10.1136/bmjqs-2013-002188.


93. Shea K.M., Hobbs A.L., Shumake J.D., et al. Impact of an antiretroviral stewardship strategy on medication error rates. Am J Health Syst Pharm. 2018;75(12):876–85. Doi: 10.2146/ajhp170420.


94. Daniels L.M., Raasch R.H., Corbett A.H. Implementation of targeted interventions to decrease antiretroviral-related errors in hospitalized patients. Am J Health Syst Pharm. 2012;69(5):422–30. Doi: 10.2146/ajhp110172.


95. Cann T., Gardner A. Change for the better: an innovative model of care delivering positive patient and workforce outcomes. Collegian. 2012;19(2):107–13. Doi: 10.1016/j.colegn.2011.09.002.


96. Gimenez-Manzorro A., Romero-Jimenez R.M., Calleja-Hernandez M.A., et al. Effectiveness of an electronic tool for medication reconciliation in a general surgery department. Int J Clin Pharm. 2015;37(1):159–67. Doi: 10.1007/s11096-014-0057-0.


97. Sanders J., Pallotta A., Bauer S., et al. Antimicrobial stewardship program to reduce antiretroviral medication errors in hospitalized patients with human immunodeficiency virus infection. Infect. Control Hosp Epidemiol. 2014;35(3):272–77. Doi: 10.1086/675287.


Об авторах / Для корреспонденции


Автор для связи: О.Д. Остроумова, д.м.н., профессор, зав. кафедрой терапии и полиморбидной патологии им. академика М.С. Вовси, Российская медицинская академия непрерывного профессионального образования; профессор кафедры клинической фармакологии и пропедевтики внутренних болезней, Первый МГМУ им. И.М. Сеченова (Сеченовский Университет), Москва, Россия; ostroumova.olga@mail.ru


ORCID / eLibrary SPIN:
Д.А. Сычев, https://orcid.org/0000-0002-4496-3680; eLibrary SPIN: 4525-7556
О.Д. Остроумова, https://orcid.org/0000-0002-0795-8225; eLibrary SPIN: 3910-6585
А.И. Кочетков, https://orcid.org/0000-0001-5801-3742; eLibrary SPIN: 9212-6010
А.П. Переверзев, https://orcid.org/0000-0001-7168-3636; eLibrary SPIN: 4842-3770
Т.М. Остроумова, https://orcid.org/0000-0003-1499-247x; eLibrary SPIN: 5043-4713
М.В. Клепикова, https://orcid.org/0000-0003-4258-1889; eLibrary SPIN: 1718-1030
Е.Ю. Эбзеева, https://orcid.org/0000-0001-6573-4169; eLibrary SPIN: 2011-6362


Похожие статьи


Бионика Медиа