Autoimmune Hepatitis And Overlap Syndromes

T.N. Lopatkina

Autoimmune hepatitis (AIG) is a relatively rare liver disease that affects primarily women of any age; it accounts 10 to 20% of the total spectrum of chronic hepatitis. The article presents modern point-based system to identify signs of AIG; clinical presentation of AIG is considered. Other variants of autoimmune liver disease are primary biliary cirrhosis (PBC) and primary sclerosing cholangitis (PSC). The overlap syndromes between different autoimmune liver diseases AIG-PBC and AIG-PSC are discussed. Modern approaches to the treatment of AIG and overlap syndromes with glucocorticoids, azathioprine, and ursodeoxycholic acid are presented.

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