CORRECTION OF EXOCRINE PANCREATIC INSUFFICIENCY IN CHRONIC BILIARY PANCREATITIS


D.I. Trukhan, L.V.Tarasova

Chronic pancreatitis (CP) is one of the most urgent and investigated problems in gastroenterology. Despite the variety of the spectrum of etiologic, pathogenetic and provoking factors for CP, one of the leading causes of disease pathology is pathology of biliary tract. A key element in treatment of CP is the correction of exocrine pancreatic insufficiency; furthermore, characteristic feature of biliary pancreatitis that distinguishes it from other forms of pancreatitis, is a combination of exocrine pancreatic insufficiency with chronic biliary insufficiency. The use of modern mini-microspheric multienzyme preparations (Creon ®) in combination with ursodeoxycholic acid significantly improves the clinical efficacy of replacement therapy.

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