Adherence in bronchial asthma and chronic obstructive pulmonary disease: from a problem to a solution


DOI: https://dx.doi.org/10.18565/pharmateca.2019.5.122-126

A.A. Vizel (1), I.Yu. Vizel (1, 2), I.N. Salakhova (1), A.R. Vafina (1)

1) Kazan State Medical University, Kazan, Russia; 2) Central Tuberculosis Research Institute, Moscow, Russia
Chronic obstructive pulmonary disease (COPD) and bronchial asthma (BA) remain the leading chronic broncho-obstructive pathology requiring lifelong use of inhaled medicines continuously or as needed depending on the severity of the disease. The key element in the treatment is the patient’s compliance with doctor’s recommendations both on drug therapy and on lifestyle and behavior, that is, adhe­rence.
A review of current positions on classification, methods of detection and methods of correcting intentional and unintentional non-adherence, as well as the results of authors’ own research of 229 patients with BA and 154 patients with COPD is presented. Authors’ own data showed higher adherence of patients with controlled BA (75.9% vs 51.2% with uncontrolled BA). In COPD, adherence was significantly lower, but patients with more pronounced impaired forced expiratory parameters had the highest frequency of adhe­rence. According to the spirometric data (GOLD-2006), only 9.1% of patients with I degree of severity adhered to medical prescriptions, with II degree – only 26.1%, with III – 25.4%, and with IV degree – 43, 3%. Treatment adherence in COPD and BA remains low, but there are methods for its improvement.

About the Autors


Corresponding author: Alexander A. Vizel, MD, Professor, Head of the Department of Phthisiopulmonology, Kazan State Medical University, Kazan, Russia; ORCID: https://orcid.org/0000-0001-5028-5276; Address: 49, Butlerova Street, Kazan 420012, Russian Federation


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