BLOOD VISCOSITY AS A TARGET OF THERAPEUTIC INTERVENTION IN CARDIOVASCULAR PATHOLOGY


V.S. Nikiforov

SBEI HPE "North-Western State Medical University n.a. I.I. Mechnikov" of RMPH, St. Petersburg
The article discusses the current state of the issue of blood viscosity at the most common cardiovascular diseases – arterial hypertension, atherosclerosis, coronary artery disease, and metabolic syndrome. The basic rheological parameters of blood affecting its fluidity - deformability and aggregation of red blood cells, hematocrit, platelet aggregation, fibrinogen, protein fractions, and lipids – are described. The role of blood and plasma viscosity in predicting mortality and cardiovascular risk is discussed. Particular attention is paid to the influence of drugs used in cardiology - statins, β-blockers, calcium channel blockers, nitrates, ACE inhibitors, diuretics - on the blood viscosity.

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About the Autors


V.S. Nikiforov- Doctor of Medical Sciences, Prof., SBEI HPE "North-Western State Medical University n.a. I.I. Mechnikov" of RMPH, St. Petersburg; e-mail: Viktor.Nikiforov@spbmapo.ru


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