VITAMIN D CONCENTRATIONS AND METABOLIC DISORDERS: SYSTEMATIC ANALYSIS OF THE FUNDAMENTAL AND EVIDENCE-BASED STUDIES ON THE PROBLEM OF OVERWEIGHT AND DIABETES MELLITUS


O.A. Gromova (1, 2), I.Yu. Torshin (2, 3), O.A. Limanova (1, 2), T.R. Grishina (1), A.N. Gromov (3)

(1) SBEI HPE "Ivanovo State Medical Academy" of RMPH, Ivanovo; (2) Russian Satellite Center of Trace Elements Institute for UNESCO, Moscow; (3) FSBIS "Computing Center n.a. A.A. Dorodnicyn" of Russian Academy of Sciences, Moscow
Vitamin D regulates glucose and fat metabolism. Vitamin D deficiency is associated with excessive accumulation of adipose tissue, glucose tolerance and insulin resistance. This article presents the results of fundamental and clinical studies confirming the relationship between vitamin D deficiency and the formation of glucose tolerance, insulin resistance, metabolic syndrome, and diabetes mellitus. Clinical studies show that vitamin D at doses of 2000, 4000 IU/day can be effective in the treatment of obesity and diabetes mellitus.

About the Autors


O.A. Gromova – MD, Prof. at the Department of Pharmacology and Clinical Pharmacology, SBEI HPE "Ivanovo State Medical Academy" of RMPH, Deputy Director for Research of the Russian Satellite Center of Trace Elements Institute for UNESCO; e-mail: unesco.gromova@gmail.com
I.Yu. Torshin – PhD in Chemical Sciences, Head of Laboratory of Computational and Systemic Biology FSBIS "Computing Center n.a. A.A. Dorodnicyn" of Russian Academy of Sciences, consultant at the Russian Satellite Center of Trace Elements Institute for UNESCO
O.A. Limanova – PhD in Medical Sciences, Associate Professor, Department of Pharmacology and Clinical Pharmacology, SBEI HPE "Ivanovo State Medical Academy" of RMPH, scientific adviser at the Russian Satellite Center of Trace Elements Institute for UNESCO
T.R. Grishina – MD, Prof., SBEI HPE "Ivanovo State Medical Academy" of RMPH
A.N. Gromov – mathematician-analyst FSBIS "Computing Center n.a. A.A. Dorodnicyn" of Russian Academy of Sciences


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