Background. In recent years, there has been a tendency towards an increase in the incidence of obesity, which inevitably leads to an increase in the prevalence of a number of associated cardiovascular and metabolic diseases. The evaluation of the features of folliculogenesis in women with obesity is an important step in studying the impact of obesity on reproductive health.
Objective. Evaluation of the parameters of folliculogenesis and their relationship with metabolic parameters in women of reproductive age.
Methods. 60 women of reproductive age were examined: 16 with normal weight or overweight, 42 with obesity of varying degrees. The following parameters were assessed in all subjects: anti-Müllerian hormone, follicle-stimulating hormone, HOMA-IR insulin resistance index, number and size of antral follicles according to ultrasound examination of the pelvic organs.
Results. The number of antral follicles significantly decreased with increasing obesity, but remained within normal values. During the assessment of correlation relationships, a strong positive correlation was confirmed between the AMH level and the number of antral follicles, between the AMH level and the FSH concentration. A negative correlation was also found between BMI and the number of antral follicles with a diameter of 6–9 mm, BMI and AMH concentration, BMI and estradiol concentration.
Conclusion. The evaluation of folliculogenesis features in obese women is an important step in studying the impact of obesity on reproductive health. Further research in this area may contribute to the development of personalized approaches to the prevention and treatment of infertility and other reproductive health disorders in overweight and obese women.

Keywords: antral follicles, ovarian reserve, anti-Mullerian hormone, insulin resistance, obesity