Prevalence, Pathogenesis And Principles Of Treatment Nonalcoholic Fatty Liver Disease

I.V. Mayev, V.V. Tsukanov, Ye.V.Lukicheva, A.A. Samsonov, A.V. Vasyutin, I.N. Nikushkina

Department of propaedeutics of internal diseases and gastroenterology, University, Moscow. Scientific research Institute of medical problems of the North, SB RAMS, Krasnoyarsk. Regional clinical hospital, Krasnoyarsk.
The article analyzed current data for the prevalence, risk factors, pathogenesis and principles of treatment of nonalcoholic fatty liver disease (NAFLD). It was concluded that NAFLD has a high prevalence in Russian population. The main risk factors for this disease are obesity, type 2 diabetes mellitus, hyperlipidemia, and metabolic syndrome. Currently, non-drug treatments of NAFLD are low-calorie diet with sufficient quantities of polyunsaturated fats and dietary fiber, graduated exercise for weight reduction. Among the drugs, insulin sensitizers, essential phospholipids, ursodeoxycholic acid and antioxidants take a leading position.

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