Place of ciclosporin A in modern therapy of rheumatoid arthritis
The article dedicated to problem of treatment of rheumatoid arthritis (RA). At the present time, cyclosporine A (CyA) – immunosuppressant with selective effect on the T-lymphocytes especially without cytotoxic effects of immunosuppression - is effective medicine of pathogenetic therapy of RA in patients poor under the standard basic therapy or in cases ineffectiveness of treatment by methotrexate. CyA regimen in RA is well established and provides a treatment monitoring. In case of insufficient response to treatment, combined therapy including using a combination of CyA with genetically engineered biological reparations is feasible.

Keywords: cyclosporin A, genetically engineered biological preparations, methotrexate, rheumatoid arthritis