Injectable lipolytics and complications from their use


DOI: https://dx.doi.org/10.18565/pharmateca.2022.14.104-110

E.V. Ikonnikova, N.E. Manturova, L.S. Kruglova, A.L. Rodina

1) Central State Medical Academy of the Administrative Department of the President of the Russian Federation, Moscow; 2) Institute of Plastic Surgery and Cosmetology, Moscow, Russia; 3) Pirogov Russian National Research Medical University, Moscow, Russia
Background. There are a lot of non-certified products on the cosmetology market, and there is no tendency to reduce the share of such low-quality drugs at the moment. It is important to be able to correctly diagnose and treat patients with complications after injectable lipolytic therapy with non-certified drugs. The article discusses the terminology, experience of injectable lipolysis, classification of lipolytics, the mechanism of action of phosphatidylcholine and deoxycholic acid, indications and contraindications for their use, topography of the method of injectable lipolysis, an overview of the most widely used lipolytics, their side reactions and complications. Description of the clinical case. A description of a clinical case of the development of an inflammatory reaction after injectable lipolytic therapy (non-certified in the Russian Federation) with an analysis of the tactics of correction the complication is given. This clinical case demonstrates the importance of using certified products. The objective reasons for the development of complications, in addition to the poor quality of the injected drug, may be inadequate injection technique (too close location of individual injections and their insufficient depth), the introduction of a large volume of lipolytic mixture, as well as non-compliance with the asepic and antiseptic regulations.

About the Autors


Corresponding author: Evgenia V. Ikonnikova, Associate Professor, Department of Dermatovenereology and Cosmetology, Central State Medical Academy of the Administrative Department of the President of the Russian Federation, Institute of Plastic Surgery and Cosmetology, Moscow, Russia; evikonnikova@bk.ru


Similar Articles


Бионика Медиа