The effectiveness of the combined use of topical glucocorticosteroid and photodynamic therapy in vulvar lichen sclerosus


DOI: https://dx.doi.org/10.18565/pharmateca.2022.14.41-47

S.I. Surkichin, L.S. Kruglova, I.A. Apolikhina

1) Polyclinic №2 of the Administrative Department of the President of the Russian Federation; 2) Central State Medical Academy of the Administrative Department of the President of the Russian Federation, Moscow, Russia; 3) National Medical Research Center For Obstetrics, Gynecology And Perinatology n.a. Academician V.I. Kulakov, Moscow, Russia
Objective. Evaluation of the effectiveness of photodynamic therapy in the treatment of vulvar lichen sclerosus (VLS), taking into account the data of the visual analogue scale using various methods of therapy.
Methods. The study included 45 women with a confirmed diagnosis of VLS. Depending on the therapy, the groups are divided into subgroups. Group 1A – patients with VLS who were prescribed topical glucocorticosteroid (tGCS), group 1B – patients with VLS who were prescribed photodynamic therapy (PDT), group 1C – patients with VLS who were prescribed combined treatment: tGCS + PDT. Results. Data obtained indicate that combination therapy with tGCS and PDT is the method of choice for the treatment of vulvar lichen sclerosus.

About the Autors


Corresponding author: Sergey I. Surkichin, Cand. Sci. (Med.), Head of the Department of Dermatovenereology and Cosmetology, Polyclinic №2 of the Administrative Department of the President of the Russian Federation; Associate Professor, Department of Dermatovenereology and Cosmetology, Central State Medical Academy of the Administrative Department of the President of the Russian Federation, Moscow, Russia; surkichinsi24@mail.ru


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