Features of examination and systemic treatment of malignant neoplasms in gerontological patients


DOI: https://dx.doi.org/10.18565/pharmateca.2021.7.138-145

T.Yu. Semiglazova (1, 2), Yu.V. Alekseeva (1), E.V. Tkachenko (1), S.M. Sharashenidze (1), I.A. Baldueva (1), S.A. Volchenkov (1), A.K. Kovyazin (1), L.V. Filatova (1, 2), B.S. Kasparov (1), V.V. Semiglazov (1, 3), S.A. Protsenko (1), V.N. Anisimov (1), A.M. Belyaev (1, 3)

1) N.N. Petrov National Medical Research Center of Oncology, St. Petersburg, Russia; 2) North-Western State Medical University n.a. I.I. Mechnikov, St. Petersburg, Russia; 3) Pavlov University, St. Petersburg, Russia
The world’s population is aging rapidly. Approximately half of all human malignant neoplasms develop in people over 65 years of age. The body of an elderly patient is influenced by three main factors – the actual malignant neoplasm, concomitant diseases and geriatric status. This necessitates the introduction of a systematic and evidence-based integrated approach, including an assessment of the geriatric status of elderly and senile cancer patients into routine clinical practice. Currently, there are many different strategies for choosing the tactics of treating patients in this category, but there are no clinical guidelines approved by Russian oncological organizations. This article presents the most important aspects of the systemic therapy of patients with solid and lymphoproliferative neoplasms in the elderly and senile age, and the main methods of complex geriatric examination.
Keywords: gerontological profile, geriatric status, complex geriatric examination, immunotherapy, targeted therapy, chemotherapy
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About the Autors

Corresponding author: Tatyana Yu. Semiglazova, Dr. Sci. (Med.), Associate Professor, Head of Department – Leading Researcher at the Scientific Department of Innovative Methods of Therapeutic Oncology and Rehabilitation, N.N. Petrov National Medical Research Center of Oncology; Professor at the Department of Oncology, North-Western State Medical University n.a. I.I. Mechnikov, St. Petersburg, Russia; tsemiglazova@mail.ru
Address: 68 Leningradskaya St., Pesochny settlement, St. Petersburg 197758, Russian Federation


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