Vitamin and mineral complex for pregnant women: modern formula

G.B. Dikke

Academy of Medical Education n.a F.I. Inozemtsev, St. Petersburg, Russia
Taking vitamin-mineral complexes (VMCs) during pregravid preparation and pregnancy improves maternal and fetal outcomes. The use of VMCs containing essential vitamins and minerals with proven efficacy in reducing the incidence of pregnancy complications is recommended, while there is a need to limit the intake of excess amount of micronutrients with unproven efficacy. Currently, both new VMCs and already well-known brands with a new composition are being produced, which reflects the search for evidence-based components and their doses. The originality of the composition of the VMC Femibion-I, -II is attributable to thee content of folic acid and metafoline in a 1:1 ratio and omega-3 docosahexaenoic acid in a separate capsule (in composition II). The addition of chelated iron in the form of bisglycinate allows avoiding side effects and achieving better tolerability, while zinc contributes to additional stimulation of hematopoiesis. Choline is a unique micronutrient (in composition I), has a positive effect on the development of the fetus and its nervous system, and Femibion is so far the only brand in Russia that contains choline.
Conclusion. Femibion-I, -II (new formula) contains essential vitamins and minerals in optimal doses proved by the results of modern research. The introduction of additional micronutrients is justified due to the high prevalence of their deficiency among pregnant women. Femibion-I differs from other VMCs due to content of choline, a unique vitamin-like substance, which has a positive effect on fetal development.

About the Autors

Corresponding author: Galina B. Dikke, Dr. Sci. (Med.), Associate Professor, Professor at the Department of Obstetrics and Gynecology with a Course in Reproductive Medicine, Academy of Medical Education n.a. F.I. Inozemtsev, St. Petersburg, Russia; e-mail:; 
Address: lit. M, 22 Moskovsky prospekt, St. Petersburg 190013, Russian Federation

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