Prevention and treatment of upper respiratory tract diseases complicating the course of acute respiratory infections


DOI: https://dx.doi.org/10.18565/pharmateca.2020.5.46-50

S.V. Morozova, L.A. Keda

Sechenov First Moscow State Medical University (Sechenov University), Department of Ear, Nose and Throat Diseases, N.V. Sklifosovsky Institute of Clinical Medicine, Moscow, Russia
Acute respiratory infections (ARI) and influenza account for up to 95% in the structure of infectious diseases. The most common pathogens for acute respiratory infections are rhinovirus, respiratory syncytial virus, adenovirus, and coronavirus. The clinical picture manifests in the form of an intoxication syndrome (fever, headache, muscle and joint pain), as well as catarrhal phenomena: hyperemia of the mucous membranes of the upper respiratory tract, and mucus overproduction. Complications of acute respiratory infections occur due to the activity of the virus or due to the secondary bacterial infection. A large proportion of the outpatient appointments in otorhinolaryngologyt accounts precisely for the late complications of acute respiratory infections. The most frequently observed manifestations of acute respiratory infections are acute rhinosinusitis, acute otitis media, tonsillopharyngitis, etc. The use of preparations containing sea water for the irrigation therapy of acute tonsillopharyngitis is high effective and safe. Studies have shown that when saline is used in the treatment of acute tonsillopharyngitis, local signs of inflammation decrease faster according to mesopharyngoscopy, with rarer occurrence of sore throat as noted by patients. Acute rhinosinusitis is one of the common complications of acute respiratory infections. Therapy of acute sinusitis should be aimed at eradicating the pathogen, relieving symptoms, as well as preventing complications. An extremely important component of the treatment of acute rhinosinusitis is irrigation and elimination therapy or sinus rinse with sea water (“nasal douche”). Nasal douche reduces the swelling of the mucous membrane and removes discharge from its surface along with viruses and bacteria. The advantage of sea water preparations over nasal decongestants includes the lack of addiction, as well as better tolerance by patients. Thus, the use of saline solutions is a high effective method for the prevention and treatment of upper respiratory tract diseases arising as a complication of acute respiratory infections. This type of treatment and prevention is well tolerated by patients, is safe and does not cause side effects.

About the Autors


Corresponding author: Svetlana V. Morozova, Dr. Sci. (Med.), Professor at the Department of Ear, Nose and Throat Diseases, Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia; e-mail: doctormorozova@mail.ru
Address: 8/2, Trubetskaya str., Moscow 119991, Russian Federation


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