Modern etiological and clinical features of acute respiratory viral infection in children. Are there any prerequisites for antiviral therapy? Literature review


DOI: https://dx.doi.org/10.18565/pharmateca.2020.1.14-19

I.N. Zakharova (1), I.M. Osmanov (2), A.N. Goryainova (1), N.V. Gavelya (2), E.V. Ruchkina (2)

1) Russian Medical Academy of Continuous Professional Education, Moscow, Russia; 2) Bashlyaeva Children’s City Clinical Hospital, Moscow, Russia
In recent years, the etiology of acute respiratory viral infections (ARVI) has expanded significantly due to the identification of new viruses, including viruses with pronounced immunosuppressive properties. When determining the treatment tactics for acute respiratory viral infections in children, it is important to consider the immaturity of their innate and adaptive immunity. The use of modern drugs with a broad antiviral and immunomodulatory effect can increase the effectiveness of antiviral protection, prevent the development of the di-sease or reduce the severity of its course. Given the high frequency of acute respiratory viral infections in children in the modern world, the development and implementation of antiviral agents that do not have cytotoxicity and have high clinical efficacy are required.

About the Autors


Corresponding author: Irina N. Zakharova, MD, Professor, Head of the Acad. G.N. Speransky Department of Pediatrics, Russian Medical Academy of Continuous Professional Education, Department of Pediatric Infectious Diseases, Moscow, Russia; e-mail: zakharova-rmapo@yandex.ru; 
ORCID: https://orcid.org/0000-0002-3367-3573; Scopus Author ID: 7102244831 
Address: 28, Heroes Panfilovtsev Street, Moscow 125373, Russian Federation


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