DIFFICULTIES IN DIAGNOSIS OF CELIAC DISEASE IN ADULTS


L.S. Oreshko, I.G. Bakulin, O.Yu. Chizhova, M.S. Zhuravleva, E.A. Semenova, E.Yu. Pavlova, Z.M. Tskhovrebova

FSBEI HE NWSMU n.a. I.I. Mechnikov of RMH, St. Petersburg, St. Petersburg
The article discusses the problem of differential diagnosis of celiac disease in adult patients is in terms of the various «clinical masks» of this disease and the laboratory-instrumental criteria for its presence. At present, extraintestinal manifestations of celiac disease in adult patients are more common than classical symptoms of malabsorption syndrome. In atypical course, extraintestinal disorders with mild gastrointestinal symptoms may be predominated in clinical presentation. As an illustration of the diagnostic search for celiac disease, two clinical cases are presented. The first of them is interesting in connection with the late manifestation of celiac disease, the predominance of articular syndrome in a clinical presentation characterized by isolated malabsorption on the background of anomaly and hypomotor function of the gallbladder. The second case is an example of an atypical course of celiac disease with predominance of pseudoallergic manifestations and late verification of the disease.

About the Autors


Corresponding author: L.S. Oreshko – MD, Prof. at the Department of Propaedeutics of Internal Diseases FSBEI HE NWSMU n.a. I.I. Mechnikov of RMH, St. Petersburg; e-mail: oreshkol@yandex.ru


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