INITIAL ANTIBACTERIAL THERAPY FOR THE TREATMENT OF ACUTE OTITIS MEDIA IN PEDIATRIC PRACTICE


A.I. Kryukov (1, 3), N.L. Kunelskaya (1, 3), A.Yu. Ivoylov (1, 2, 3), I.I. Arkhangelskaya (1)

1) SBHCI «Scientific Research Clinical Institute of Otorhinolaryngology n.a. L.I. Sverzhevsky» of Moscow Healthcare Department; 2) SBHCI «Children’s City Clinical Hospital № 9 n.a. G. N. Speransky» of Moscow Healthcare Department; 3) FSBEI HPE «Russian National Scientific Medical University n.a. N.I. Pirogov» of RMH, Moscow
Acute otitis media (AOM) is one of the most common diseases in children and is one of the reasons for the appointment of systemic antibacterial therapy. Taking into account typical pathogens (Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis) and Russian data on antibiotic resistance, the drug of first choice in AOM is amoxicillin, which has a high stable activity against the abovementioned major bacterial pathogens. Due to the high level of resistance of pneumococcus to penicillins in many countries of the world, it is recommended to use high doses of the drug (80–90 mg/kg/day), which create concentrations exceeding the MIC for strains with an intermediate level of resistance. The tactics and duration of antibacterial therapy in case of AOM are discussed.

About the Autors


Corresponding author: A.Yu. Ivoylov – MD, Head of the Department of ENT Pathology of Childhood SBHCI «Scientific Research Clinical Institute of Otorhinolaryngology n.a. L.I. Sverzhevsky» of Moscow Healthcare Department, Head of the Department of Otorhinolaryngology SBHCI «Children’s City Clinical Hospital № 9 n.a. G. N. Speransky» of Moscow Healthcare Department, Prof. at the Department of Otorhinolaryngology of the Pediatric Faculty FSBEI HPE RNSMU n.a. N.I. Pirogova of RMH, Moscow, tel. 8 (499) 259-99-12; e-mail: 14lor@mail.ru


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