CITICOLINE IN THE COMPLEX OF EARLY REHABILITATION OF PATIENTS WITH ISCHEMIC STROKE


E.A. Petrova (1, 2), E.A. Koltsova (1, 2), V.V. Gudkova (2), L.V. Stakhovskaya (1, 2)

(1) SRI of Cerebrovascular Pathology and Stroke FSBEI HE RNSMU n.a. N.I. Pirogov of RMH, Moscow (2) Department of Fundamental and Clinical Neurology and Neurosurgery FSBEI HE RNSMU n.a. N.I. Pirogov of RMH, Moscow
The review is devoted to the use of Ceraxon® (citicoline) in a complex of therapeutic and rehabilitation measures in patients with acute ischemic stroke. The results of numerous experimental and clinical studies of the effect of citicoline on ischemia and cerebral hypoxia are presented. The main pharmacological properties of citicoline, which has a complex neuroprotective effect, are described. Data of most recent multicenter placebo-controlled trials of the use of this drug in acute stroke are presented. The basic principles of successful neurorehabilitation in stroke are discussed – early start, continuity, multidisciplinary organizational approach, combination of rehabilitation measures and drug support of neuroplasticity.

About the Autors


Corresponding author: E.A. Petrova – SRI of Cerebrovascular Pathology and Stroke FSBEI HE RNSMU n.a. N.I. Pirogov of RMH, Moscow; e-mail: 6332011@mail.ru


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