D.Sh. Macharadze (1), V.I. Peshkin (1), T.A. Zolotareva (2)

(1) SBEI HPE "People’s Friendship University of Russia", Moscow; (2) SBHCI "City Children's Polyclinic № 132" of the Moscow Healthcare Department
Treatment of atopic dermatitis (AD) is based on arresting two cardinal signs of the disease - dryness and itching of the skin. For this purpose, patients requires routinely use of emollients and topical anti-inflammatory drugs - corticosteroids and/or calcineurin inhibitors. However, there are studies strongly supporting the presence of subclinical inflammation, accompanied by disturbances of skin barrier function, cytokine production and lymphocyte infiltration. The new strategy of therapy - proactive therapy – is aimed to achieving control and maintenance of remission of atopic dermatitis. This will allow to achieve control of AD faster and to reduce the risk of recurrence of the disease.


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About the Autors

D.Sh. Macharadze – MD, Prof. at the Department of Allergology and Clinical Immunology PFUR, Moscow

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