COMPREHENSIVE TREATMENT OF ERECTILE DYSFUNCTION IN MEN WITH OBESITY


A.S. Ametov, M.V. Stelmakh

Department of Endocrinology and Diabetology SBEI FPE RMAPE of RMPH, Moscow
Obesity is one of the most important public health problems due to its common association with many chronic diseases, including metabolic syndrome, type 2 diabetes mellitus, cardiovascular diseases, and dyslipidemia. In addition, obesity is associated with a high prevalence of erectile dysfunction (ED), but the pathophysiological relationships between these conditions are still poorly understood. Along with drugs aimed at the normalization of erection, therapy promoting weight loss should play a major role in the treatment of erectile dysfunction in obese men. Treatment of erectile dysfunction and obesity should be carried out simultaneously, as the simultaneous existence of these two pathologies support depression, which significantly worsens the prognosis of treatment. Therefore, men with obesity and ED need combination therapy aimed at reducing body weight and sexual dysfunction. In the current study, the findings suggest the positive effect of weight loss, and consequently – decrease of the impact of the lipotoxicity phenomenon on androgenic status of obese men. It has been shown that the program for the reduction of body weight is not effective and that men with obesity and erectile dysfunction require drug therapy.

About the Autors


A.S.Ametov – MD, Prof., Head of the Department of Endocrinology and Diabetology SBEI FPE RMAPE of RMPH
M.V. Stelmakh – endocrinologist, postgraduate student at the Department of Endocrinology and Diabetology SBEI FPE RMAPE of RMPH; e-mail: mariastel@mail.ru


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