CETRINE IN THE CLINICAL PRACTICE OF TREATING CHILDREN WITH ALLERGIC DISEASES


V.A. Revyakina

Department of Allergology FSBI SRI of Nutrition RAMS, Moscow
The article presents the modern data on the mechanisms of action and potentials for the use of antihistamines, primarily cetirizine, in the treatment of allergic diseases. The results of application of a generic Cetrine (cetirizine) in the therapy of 27 children (10 boys, 17 girls) aged 2-9 years with mild-to-moderate atopic dermatitis with disease duration of 3-5 years are discussed. In addition to Cetrine, patients have received topical glucocorticosteroid (GCS) mometasone furoate. Maximum duration of use of topical GCS therapy was 7 days, and minimal symptoms of the disease in 11 patients were controlled by receiving Cetrine only. At Day 10, the remission of AD was achieved in 23 children; exacerbation of disease was arrested in all patients at the end of the 2nd week. Follow-up for 2-4 months showed that 21 (77.8%) patients achieved long-term remission of atopic dermatitis, and 6 patients had one episode of mild exacerbation.

About the Autors


RevyakinaV.A . – MD, Prof., Head of the Department of Allergology FSBI SRI of Nutrition RAMS


Similar Articles


Бионика Медиа