Фармакологическое действие и клиническое применение цитиколина: обзор экспериментальных данных и клинических исследований


DOI: https://dx.doi.org/10.18565/pharmateca.2019.13.91-95

М.Е. Сергиенко

Дорожная клиническая больница на ст. Челябинск ОАО РЖД, Челябинск, Россия
Цитидин 5-дифосфохолин (ЦДФ-холин, или цитиколин) является незаменимым промежуточным веществом в биосинтезе структурных фосфолипидов в клеточных мембранах, в частности фосфатидилхолина. Обзор посвящен исследованиям препарата цитиколин. Освещены экспериментальные данные его влияния на травматическое повреждение и экспериментальный отек головного мозга, а также результаты клинического применения при черепно-мозговой травме и ее последствиях.
Ключевые слова: цитиколин, ацетилхолин, черепно-мозговая травма, отек головного мозга, посттравматические нарушения памяти

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Об авторах / Для корреспонденции


Автор для связи: М.Е. Сергиенко, врач-невролог, врач высшей квалификационной категории, Дорожная клиническая больница на ст. Челябинск ОАО РЖД, Челябинск, Россия; e-mail: smarfor@mail.ru
Адрес: 454091, Россия, Челябинск, ул. Цвиллинга, 41


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