Биологические препараты в терапии воспалительных заболеваний кишечника: реальность и перспективы


М.И. Скалинская (1), И.Г. Бакулин (1), Е.В. Сказываева (1), Т.Н. Жигалова (1), К.Н. Рындин (1), М.В. Соловьев (2)

1) ФГБОУ ВО СЗГМУ им. И.И. Мечникова, Санкт-Петербург; 2) ФГБВОУ ВО «Военно-медицинская академия им. С.М. Кирова» МО РФ, Санкт-Петербург
Этиология воспалительных заболеваний кишечника (ВЗК) неизвестна, а патогенез понятен не в полном объеме. На сегодняшний день для пациентов с ВЗК в Российской Федерации доступны моноклональные антитела к фактору некроза опухоли α и антитела против α4–β7. Но в настоящее время в мире активно развивается направление таргетной терапии: накапливается опыт применения первых препаратов, продолжается поиск новых молекул, способных прерывать воспалительный каскад и одновременно с этим имеющих высокий профиль безопасности.

Литература


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Об авторах / Для корреспонденции


Автор для связи: М.И. Скалинская – к.м.н., доцент кафедры пропедевтики внутренних болезней, гастроэнтерологии и диетологии ФГБОУ ВО СЗГМУ им. И.И. Мечникова Минздрава России, mskalinskaya@yahoo.com


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