Rational Therapy Of Cough In Infectious And Inflammatory Respiratory Diseases In Children

A.L. Zaplatnikov, A.A. Girina, N.V. Koroid, N.S. Glukhareva

The article is devoted to the cough as one of the most frequent and persistent symptoms occurring in respiratory infections in children. The data on the pathogenesis are presented, clinical features of this symptom and principles of therapy are discussed. Currently, there is a large arsenal of antitussive drugs. In each case, the choice of drugs should be based on a complex of objective data (pathogenesis and clinical features of the disease, the individual characteristics of the child, pharmacodynamics and pharmacokinetics of the drug, etc.). Particular attention is paid to non-narcotic antitussive drug butamirate (Sinecod) having high clinical efficacy and safety for using in children from 2 months of age. Sinecod not only has antitussive effect, but moderate anti-inflammatory effect, and contributes to moderate bronchodilation and reduced airway resistance, which determines the potentiation of the therapeutic effect.

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