In accordance with the EULAR recommendations (2003) for the treatment of osteoarthritis (OA), so-called slow-release symptom-modifying drugs with a possible structure-modifying activity (chondroprotectors) and preparations for intra-articular injection are widely used. We present results of study focused on the effectiveness of treatment of OA of stifle joint. Study included 40 patients with OA aged 53-70 years, all patient received chondroprotector Artra in combination with intra-articular injection of Alflutop. Initially we assessed arthrological status of patients after the end of treatment and at 6 months later, X-ray study and ultrasound investigation of the stifle joint were performed in accordance with the EULAR recommendations. After treatment pain reduction by 15%, improvement in summed score for WOMAC pain subscale by 20%, stiffness subscale – by 18% function subscale – by 25%, and decrease of index Lekena by 22% were observed. Data for slowing radiological progression of OA were not obtained, perhaps due to of the small period of observation.

Keywords: artra, alflutop, chondroprotectors, glucosamine, chondroitin sulfate, osteoarthritis