Distal polyneuropathy is the most frequent complication of diabetes and alcoholism in patients with a long history of underlying disease, particularly when the course of disease is uncontrolled. In recent years, prevention and treatment of neuropathy are under steadfast attention, since the affection of the peripheral nervous system in such patients leads to a severe pain syndrome and reduce quality of life, and in severe cases, contributes to depression and disability. Currently, physicians have effective drugs influencing the pathogenic mechanisms and symptoms of polyneuropathy. One of them is Neuromultivit, combined medication, including high doses of B vitamins (thiamine, pyridoxine, cyanocobalamin).

Keywords: B vitamins, alcoholism, polyneuropathy, diabetes mellitus