New achievements in the treatment of chronic obstructive pulmonary disease (results of the UPLIFT study)
The article discusses the problem of chronic obstructive pulmonary disease (COPD) progression as well as the results of large randomized clinical study UPLIFT studied the long-term effect of tiotropium bromide on pulmonary function in COPD patients. The drug has a high clinical efficacy and safety, reduces mortality from cardiovascular and respiratory complications, and provides sustained improvement of pulmonary function without changing of annual decline rate within 4 years. The tiotropium bromide administration can be recommended as a long-term maintenance therapy in all patients with COPD.

Keywords: tiotropium bromide, bronchodilators, UPLIFT study, chronic obstructive pulmonary disease (COPD), quality of life