Therapeutic use of amaranth oil: current trends and prospects of use


DOI: https://dx.doi.org/10.18565/pharmateca.2025.4.42-47

Mubarakshina O.A., Batishcheva G.A., Zhdanova O.A., Volynkina A.P., Grechushkina I.V.

1) Voronezh State Medical University named after N.N. Burdenko, Voronezh, Russia; 2) Voronezh City Polyclinic No. 10, Voronezh, Russia
In recent years, there has been a growing interest in the use of plant products as effective means of preventing and treating various diseases. In this regard, it is of interest to study the pharmacological properties and therapeutic effects of amaranth oil. An important active ingredient of this product is squalene, which has antioxidant, regenerating, immunomodulatory, hypocholesterolemic effects. Other components of amaranth oil act in synergy with squalene: polyunsaturated fatty acids, phospholipids, vitamin E, etc. The presence of these biologically active compounds justifies the use of amaranth oil in various diseases, including chronic venous insufficiency, cardiovascular diseases, type 2 diabetes mellitus and a number of other pathologies. Modern technology for extracting oil from amaranth germs provides a high concentration of beneficial nutrients and preservation of all pharmacological properties. Available experimental and clinical data allow to recommend amaranth oil as an effective supplement to traditional methods of treatment and prevention of various diseases.
Keywords: hepatoprotective effect, lipid-lowering effect, squalene, amaranth oil, amaranth seed oil, antioxidant effect, chronic venous insufficiency, type 2 diabetes mellitus, microcirculation
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About the Autors

Olga A. Mubarakshina, Cand. Sci. (Med.), Associate Professor, Department of Clinical Pharmacology, Voronezh State Medical University named after N.N. Burdenko, Voronezh, Russia; mubarakshina@mail.ru, ORCID: https://orcid.org/0000-0001-6799-6322 (corresponding author)
Galina A. Batishcheva, Dr. Sci. (Med.), Professor, Head of the Department of Clinical Pharmacology, Voronezh State Medical University named after N.N. Burdenko, Voronezh, Russia; bat13@mail.ru, ORCID: https://orcid.org/0000-0003-4771-7466
Olga A. Zhdanova, Dr. Sci. (Med.), Associate Professor, Professor, Department of Clinical Pharmacology, Voronezh State Medical University named after N.N. Burdenko, Voronezh, Russia; olga.vr9@yandex.ru, ORCID: https://orcid.org/0000-0002-3917-0395
Anna P. Volynkina, Cand. Sci. (Med.), Associate Professor, Department of Hospital Therapy and Endocrinology, Voronezh State Medical University named after N.N. Burdenko, Voronezh, Russia; ovp.idpo@vrngmu.ru, ORCID: https://orcid.org/0000-0001-8942-6224
Irina V. Grechushkina, Cand. Sci. (Med.), General Practitioner, Day Hospital, Voronezh City Polyclinic No. 10, Voronezh, Russia;
irina1984grechushkina@gmail.com, ORCID: https://orcid.org/0009-0004-6815-8151


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