New trends in kidney tumor diagnostics (literature review)
DOI: https://dx.doi.org/10.18565/pharmateca.2024.7.27-32
A.V. Khasigov, V.T. Tebiev, A.V. Timoshenkova
North Ossetian State Medical Academy, Vladikavkaz, Russia
Renal cell carcinoma (RCC) is one of the most common oncourological diseases and ranks 10th among malignant neoplasms in the world and 3rd among malignant neoplasms of the genitourinary system (EAU Guidelines, 2017). According to B.P. Matveev (2011), over the past decades, there has been a tendency to increase RCC by 2–4% per year in all population groups. This is attributable to both a true increase in a number of oncourological patients and the improvement of modern diagnostic capabilities. However, despite a significant number of patients with early identified tumor process, the mortality rate from the disease remains high. The only effective method of treating RCC is surgery, which involves nephrectomy or resection of the kidney with the tumor, but in 68.1% of patients with localized and locally advanced forms of the disease, according to B.P. Matveev (2011), tumor process progresses after radical treatment at various times. High incidence rate, large number of relapses, variability of the course of the tumor process after surgery and the lack of a single prognostic system with high accuracy determine the relevance of the problem and indicate the need to create a prognostic panel of factors that can accurately predict the course of the disease after surgery for RCC. The objective of the review is to determine the diagnostic value of CT angiography and CT perfusion in optimizing surgical treatment tactics and assessing the functional capacity of the renal parenchyma in RCC. The search results in the PubMed, Medline, Web of Science scientific databases for the queries «renal parenchyma cancer», «diagnosis of kidney tumors» were analyzed. The review provides detailed consideration and illustration of prognostic factors for the course of the disease in locally advanced renal cancer and the diagnostic value of CT angiography and CT perfusion in determining tumor invasion of intrarenal vessels.
Conclusion. Despite the long history of studying renal parenchymal cancer, there are still no reliable data on the diagnosis of kidney tumors and various prognostic factors for the course of RCC, therefore, the article analyzes and collects the results of recent studies.
About the Autors
Corresponding author: Alan V. Khasigov, North Ossetian State Medical Academy, Vladikavkaz, Russia; alan_hasigov@mail.ru
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