Asthenia is a pathological condition that can accompany various diseases and also develop in healthy individuals under certain circumstances. Unlike ordinary fatigue, which, as a rule, occurs as a result of intense mobilization of the body and is a physiological condition, asthenia does not disappear after rest and requires medical assistance. Correction of asthenia symptoms is an urgent task in the clinical practice of outpatient doctors. The article discusses the main clinical manifestations of asthenic syndrome and its features, pathogenetic mechanisms of development, and the possibilities of non-drug and drug treatment. A promising treatment strategy for patients is the use of the phenylpiracetam.

Keywords: MFI-20 asthenia scale, weakness, pathological fatigue, phenylpiracetam, asthenia, asthenic syndrome, fatigue