Objective. Systematic analysis of the data available in modern literature on the possibilities of non-hormonal correction of menopausal syndrome.
Basic provisions. Menopausal syndrome is characterized by a symptom complex that includes vegetative-vascular, mental and metabolic-endocrine disorders as result of a single pathogenetic process caused by estrogen deficiency and subsequent dysfunction of the hypothalamic-pituitary system. If there are contraindications and concerns about the safety of the use of menopausal hormone therapy, it is possible to use alternative non-hormonal agents to relieve the symptoms of menopausal syndrome.
Conclusion. Based on the analysis of literary sources, modern data regarding current methods of non-hormonal correction of menopausal disorders in women during peri- and postmenopause were summarized.

Keywords: irritability, hot flashes, alternative therapy, menopausal hormone therapy, menopause, postmenopause