Modern treatment options for arrhythmias: focus on propafenone
DOI: https://dx.doi.org/10.18565/pharmateca.2023.9-10.104-108
A.I. Tarzimanova
Sechenov University, Moscow, Russia
Cardiac rhythm disturbances are among the most common syndromes in the clinic of internal medicine. The development of arrhythmias is almost always accompanied by a deterioration in the quality of life, and the development of ventricular cardiac arrhythmias increases the risk of a poor prognosis. Propafenone deserves special attention among the many modern antiarrhythmics as one of the most effective and safe drugs. The pharmacodynamics of propafenone allows it to be used as a loading dose when taken orally and used for the relief of paroxysms of atrial fibrillation and a wide range of supraventricular cardiac arrhythmias in outpatient settings by patients independently. To maintain sinus rhythm in patients without severe structural pathology of the heart, both with supraventricular rhythm disturbances and with ventricular extrasystole, propafenone can be used for a long time, without interruptions.
About the Autors
Corresponding author: Aida I. Tarzimanova, Dr. Sci. (Med.), Professor at the Department of Faculty Therapy № 2, Sechenov University, Moscow, Russia; phone: +7 (495) 245-45-32, tarzimanova@mail.ru; ORCID: https://orcid.org/0000-0001-9536-8307
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