Systemic lupus erythematosus in the practice of a pulmonologist


I.N. Trofimenko, A.A. Kiseleva, O.D. Tiguntseva, N.V. Blagoveshchenskaya

1) Irkutsk State Medical Academy of Postgraduate Education – Branch Campus of the Russian Medical Academy of Continuous Professional Education, Department of Clinical Allergology and Pulmonology, Irkutsk, Russia; 2) Irkutsk Order “Badge of Honor” Regional Clinical Hospital, Irkutsk, Russia
Background. Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease with a wide range of pleuropulmonary lesions. Acute lupus pneumonitis (ALP) is one of the rare complications of SLE.
Description of the clinical case. A clinical case of ALP after delivery as an initial manifestation of SLE in 24-year-old woman is pre- sented. In the case described, lupus pneumonitis developed against the background of high SLE activity and was characterized by fever, acute onset of respiratory symptoms, accompanied by the development of respiratory failure. Difficulties in diagnosing ALP were associated to the nonspecificity of clinical and radiological manifestations and the lack of an established diagnosis of SLE at the time of development of acute respiratory failure.
Conclusion. The high risk of death requires early diagnosis and timely therapy. ALP is a diagnosis of exclusion and needs to be dif- ferentiated from infectious and other non-infectious complications of SLE. In the presented case, clinical, radiological and functional improvements were noted after combined pulse therapy.

About the Autors

Corresponding author: Irina N. Trofimenko, Dr. Sci. (Med.), Associate Professor, Head of the Department of Clinical Allergology and Pulmonology, Irkutsk State Medical Academy of Postgraduate Education, Irkutsk, Russia;; ORCID:; eLibrary SPIN: 9345-4572

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