The review presents some clinical situations in children of the first year of life, in which dimetindene maleate can be prescribed: non-anaphylactic allergic reactions to food or drugs, atopic dermatitis, food protein-induced enterocolitis, some infectious skin diseases. Dimetindene maleatebelongs to the 1st generation antihistamines, and its licensed use according to indications is allowed for children aged 1 month or older. The rationale for the use of antihistamines is the relief of histamine-mediated symptoms as adjunctive therapy in various diseases. To achieve the optimal clinical effect, it is important to use dimetindene maleate correctly, taking into account the dosing interval and dosage of the drug, as well as its possible side effects.

Keywords: dimetindene maleate, pruritus, antihistamines