Postoperative management of patients after transnasal endoscopic sinus surgery


DOI: https://dx.doi.org/10.18565/pharmateca.2021.5.109-114

M.A. Edzhe, E.V. Marasanova, A.Yu. Ovchinnikov

A.I. Yevdokimov Moscow State University of Medicine and Dentistry, Department of Otorhinolaryngology, Moscow, Russia
Background. Endoscopic transnasal sinus surgery is the method of choice in the treatment of the vast majority of pathology of paranasal sinuses requiring surgery. An important part in achieving clinical effect is the management in the postoperative period. In this regard, it remains relevant to study various treatment regimens with the justified inclusion of certain drugs.
Objective. Evaluation of the effectiveness of nebulizer therapy in patients after endoscopic transnasal sinus surgery.
Methods. 141 patients were followed-up. There were 90 (63.83%) men and 51 (36.17%) women. The patients’ age ranged from 25 to 66 years (mean age – 49.3±12.5 years). Depending on the tactics of postoperative management, the patients were randomized into two groups. The main group (MG) of patients underwent an original method of postoperative rehabilitation. The comparison group (CG) did not receive it.
Results. According to the results obtained, on the 14th and 30th days of treatment, the severity of subjective and objective symptoms, presented in points, significantly decreased in both groups and there were no statistically significant differences between the mean values (p>0.05). A different situation was noted after 3-month course of prescribed therapy – on the 4th month and after 1 year follow-up, when, despite the improvement of clinical symptoms in CG, positive dynamics was significantly better in MG (p<0.05).
Conclusion. The study has demonstrated the effectiveness of the proposed scheme for postoperative manegement of patients after endoscopic transnasal sinus surgery. This treatment regimen is characterized by the absence of side effects and allows to achieve rehabilitation of patients in a shorter time.

About the Autors


Corresponding author: Maya A. Edzhe, Cand. Sci. (Med.), Associate Professor at the Department of Otorhinolaryngology, A.I. Yevdokimov Moscow State University of Medicine and Dentistry, Moscow, Russia; ayam75@mail.ru
Address: build. 1, 20 Delegatskaya St., Moscow 127473, Russian Federation


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