Ya.A. Petrosyan, T.R. Mamedova, A.G. Syrkasheva, E.A. KalininaV.I. Kulakov National Medical Research Center of Obstetrics, Gynecology and Perinatology, Moscow, Russia
Background. The increase in the number of patients with infertility and the lack of ovarian reserve contributed to the development of a new trend in reproductive medicine - in vitro fertilization (IVF) with donor oocytes. Description of the clinical case. A clinical observation of a 50-year-old female patient who applied for an IVF program due to secondary infertility due to a lack of ovulation as a result of persistent physiological menopause, as well as a male factor is presented. Given the inability to obtain her own oocytes, it was decided to conduct an IVF program with donor oocytes. At the first stage, cyclic hormone therapy was prescribed to restore the menstrual cycle. After 3 months, an IVF program with donor oocytes was performed. Fertilization of 4 donor oocytes by the seminal fluid of the spouse by the PICSI method (intracytoplasmic injection of a spermatozoon selected on a physiological basis) was performed. Preparation of the endometrium in the embryo transfer cycle was carried out using estrogens and gestagens. The IVF program ended with the onset of clinical pregnancy and timely delivery. Conclusion The IVF program with donor oocytes allows for the implementation of reproductive function in various categories of patients, including with persistent menopause.
For citations: Petrosyan Ya.A., Mamedova T.R., Syrkasheva A.G., Kalinina E.A. IVF program with donor oocytes for a woman in
persistent postmenopause: clinical observation. Farmateka. 2019;26(6):106–10. (in Russian). DOI: https://dx.doi.org/10.18565/pharmateca.2019.6.106-110
Corresponding author: Anastasiya G. Syrkasheva, PhD, Senior Researcher of B.V. Leonov IVF Department of Auxiliary Technologies in Infertility Treatment, Academician V.I. Kulakov Research Center of Obstetrics, Gynecology and Perinatology, Moscow, Russia; tel. +7(495) 438-13-41, e-mail: firstname.lastname@example.org
Address: 4, Akademik Oparin Street, Moscow 117997, Russian Federation