ATORVASTATIN IN THE PREVENTION OF CARDIOVASCULAR DISEASES IN FEMALE PATIENTS WITH RHEUMATOID ARTHRITIS


S.A. Smakotina (1), A.R. Zelendinova (1), I.N. Bondareva (2), N.V. Fomina (1), S.A. Berns (3), A.A. Golikova (3)

(1) Kemerovo State Medical University, Kemerovo (2) Kemerovo Regional Clinical Hospital, Kemerovo (3) FSBEI HE MSMSU n.a. A.I. Evdokim of RMH, Moscow
Cardiovascular accidents are the main cause of mortality in rheumatoid arthritis (RA). The use of statins can be a key for the successful prevention of cardiovascular complications in RA due to hypolipidemic and anti-inflammatory effects. The article presents the results of evaluation of the effect of atorvastatin on laboratory inflammatory parameters in female patients with RA without a history of cardiovascular disease, and assessment of a 2-year prognosis for the development of cardiovascular pathology. It is shown that the use of atorvastatin in addition to the disease-modifying anti-inflammatory drugs can prevent the development of hypertension, normalizes the lipid spectrum, and reduces the inflammatory activity of the disease.

About the Autors


Corresponding author: S.A. Berns – MD, Prof. at the Department of Internal Diseases of the Stomatological Faculty FSBEI HE MSMSU n.a.
A.I. Evdokimof RMH, Moscow; e-mail: svberns@yandex.ru


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