NSAID-INDUCED GASTROPATHIES: PATHOGENETICALLY SUBSTANTIATED APPROACHES TO PREVENTION AND THERAPY


I.V. Maev, D.N. Andreev, D.T. Dicheva, E.V. Partsvania-Vinogradova

SBEI HPE MSMSU n.a. A.I. Evdokimov of RMPH, Moscow
Non-steroidal anti-inflammatory drug- induced gastropathy (NSAID-gastropathy) often occurs in clinical practice due to wide use of this group of drugs. Currently, the most common of the therapeutic strategies applied considered are combination of NSAIDs with proton pump inhibitors, and the use of selective cyclooxygenase-2 inhibitors. The introduction of the new drug with proven effect, rebamipide, having a gastroprotective action by increasing the production of endogenous prostaglandins, opens up new prospects for management of this difficult group of patients in clinical practice.

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About the Autors


D.N. Andreev – Teaching Assistant of the Department of Propedeutics of Internal Diseases and Gastroenterology MSMSU n.a. A.I. Evdokimov of RMPH, Moscow; e-mail: dna-mit8@mail.ru


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