"RESPONSIBLE SELF-TREATMENT" OF PATIENTS WITH HEARTBURN


V.I. Simanenkov, S.V. Tikhonov

Department of Therapy and Clinical Pharmacology of the Northwestern State Medical University n.a. I.I. Mechnikov, St. Petersburg
This article is devoted to the concept of "responsible self-treatment" of patients with heartburn and discusses the requirements for OTC (OTC; Over-the-Counter) drugs, and compares various schemes of symptomatic therapy using antacids, H2-blockers, prokinetics, and proton pump inhibitors. Based on the pharmacokinetic and pharmacodynamic characteristics and results of clinical trials, the efficacy and safety of different proton pump inhibitors used in the "responsible self-treatment" of patients with reflux disease are characterized.

About the Autors


V.I. Simanenkov – MD, Prof., Head of the Department of Internal Diseases and Clinical Pharmacology of the Northwestern State Medical University n.a. I.I. Mechnikov
S.V. Tikhonov – Teaching Assistant at the Department of Internal Diseases and Clinical Pharmacology of the Northwestern State Medical University n.a. I.I. Mechnikov


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