IMPACT OF NITROGLYCERIN ON PACEMAKER ACTIVITY OF THE SINUS NODE IN PATIENTS WITH ANGINA PECTORIS III - IV FUNCTIONAL CLASSES


E.A. Safronova

The article presents the data on peripheral autonomic pharmacodynamics of nitroglycerin, estimated by rhythmocardiography in patients with angina pectoris III-IV functional classes. Enhancement of humoral and sympathetic influence in the sinus node under the influence of nitroglycerin through inhibition of parasympathetic regulation was revealed, and more pronounced effect was observed in patients with angina pectoris III-IV functional classes without concomitant hypertension.

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