CLINICAL PATHOMORPHOLOGICAL VERSIONS OF HEART DISEASE IN PATIENTS WITH SYSTEMIC VASCULITIS AND FEATURES OF NON-INVASIVE DIAGNOSTIC METHODS


L.A. Strizhakov, S.V.Moiseev, E.N. Semenkova, E.A. Cogan, S.P. Pasha, E.I. Kuznetsova, V.E. Ditterle, N.A. Mukhin

The article presents the results of the analysis of the incidence of cardiovascular complications and risk factors for atherosclerosis in 321 patients with systemic vasculitis (SV; Takayasu arteritis, polyarteritis nodosa, Churg-Strauss syndrome, and Wegener's granulomatosis). The features of non-invasive methods of radiation diagnosis - myocardial perfusion scintigraphy with technetium-99 and multislice computed tomography of the coronary arteries – are evaluated. The data of morphological examination of the heart and blood vessels in 55 patients are analyzed. Heart disease occurs in all forms of the SV clinical entities studied, largely determining the clinical picture of the disease and its prognosis. The combination of the traditional risk factors for atherosclerosis and SV allows to refer such patient to the ultra-high cardiovascular risk group.

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